FluoSite Anti-CD30, FITC-Labeled Antibody

This anti-CD30 antibody is a purified monoclonal recombinant antibody, which is labeled with fluorescein isothiocyanate (FITC). This antibody has been tested by flow cytometry for binding to human CD30 on transiently transfected HEK293 cells. FluoSite(TM) is a tag-based method for site-specific conjugation of antibodies with fluorophores, ensuring the labeling site is far from the antigen-binding domain to preserve antibody functionality. This precise, consistent labeling ensures the homogeneity of the labeled antibody preparation, making it ideal for flow cytometry and other high-sensitivity applications. CD30, also known as TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily Member 8), is a cell crucial surface receptor from the TNF receptor family, expressed on activated immune cells and notably upregulated in specific lymphomas like Hodgkin Lymphoma (HL) and Anaplastic Large Cell Lymphoma (ALCL). CD30 serves as a vital diagnostic marker and therapeutic target for these cancers, influencing cell survival, proliferation, and apoptosis, with its ligand being CD30L (CD153).