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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ATA-HPA035234.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
ATA-HPA035234.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: DNA annealing helicase and endonuclease required to maintain genome stability... more
Product information "Anti-ZRANB3"
Protein function: DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events (PubMed:21078962, PubMed:22704558, PubMed:22705370, PubMed:22759634, PubMed:26884333). Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase (PubMed:22759634). In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks (PubMed:22705370, PubMed:22704558). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 80% and to rat: 82%
Keywords: | Anti-AH2, Anti-Endonuclease ZRANB3, Anti-Annealing helicase 2, Anti-DNA annealing helicase ZRANB3, Anti-DNA annealing helicase and endonuclease ZRANB3, Anti-Zinc finger Ran-binding domain-containing protein 3 |
Supplier: | Atlas Antibodies |
Supplier-Nr: | HPA035234 |
Properties
Application: | ICC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: AVDNEGNPLC LRCQQPTCQT KQACKANSWD SRFCSLKCQE EFWIRSNNSY LRAKVFETEH GVCQLCNVNA QELFLRLRDA PKSQRKNLLY ATWT (ATA-APrEST89336) |
Database Information
UniProt ID : | Q5FWF4 | Matching products |
Gene ID | GeneID 84083 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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