Anti-ZNRF3 / Zinc/RING finger protein 3

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-RQ7436 100 µg - -

7 - 12 business days*

790.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Enables frizzled binding activity and... more
Product information "Anti-ZNRF3 / Zinc/RING finger protein 3"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Enables frizzled binding activity and ubiquitin-protein transferase activity. Involved in cellular protein metabolic process and negative regulation of Wnt signaling pathway. Is integral component of plasma membrane. Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby restricting the size of the intestinal stem cell zone (PubMed:22575959). Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification. [The UniProt Consortium]
Keywords: Anti-ZNRF3, Anti-KIAA1133, EC=2.3.2.27, Anti-RING finger protein 203, Anti-Zinc/RING finger protein 3, Anti-E3 ubiquitin-protein ligase ZNRF3, Anti-RING-type E3 ubiquitin transferase ZNRF3, ZNRF3 Antibody / Zinc/RING finger protein 3
Supplier: NSJ Bioreagents
Supplier-Nr: RQ7436

Properties

Application: WB, IF, FC, Direct ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: E. coli-derived recombinant human protein (amino acids R54-E913)
Format: Posttranslational Mod.

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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