Anti-ZNRF1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA027470.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA027470.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL,... more

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Product information "Anti-ZNRF1"

Protein function: E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes neurodegeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 followed by destabilization of microtubule assembly in axons (Probable). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 97%

Keywords:	Anti-ZNRF1, Anti-NIN283, EC=2.3.2.27, Anti-Zinc/RING finger protein 1, Anti-E3 ubiquitin-protein ligase ZNRF1, Anti-Nerve injury-induced gene 283 protein, Anti-RING-type E3 ubiquitin transferase ZNRF1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA027470

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: ASDSTYAHGN GYQETGGGHH RDGMLYLGSR ASLADALPLP IAPRWFSSHS GFKCPICSKS VASDEMEMHF I (ATA-APrEST76075)