Item number Size Datasheet Manual SDS Delivery time Quantity Price
A305-177A-T 20 µl (2 blots) -

3 - 9 business days

A305-177A-M 100 µl (10 blots) -

3 - 9 business days

A305-177A 100 µl (100 µg) -

3 - 9 business days

Protein function: E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates... more
Product information "Anti-ZNF451"
Protein function: E3 SUMO-protein ligase, has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494). Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro). Required for MCM4 sumoylation. Has no activity with SUMO1 (PubMed:26524493). Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site 'Lys-11' (PubMed:26524493). Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling. Inhibits EP300- mediated acetylation of histone H3 at 'Lys-9' (PubMed:24324267). Plays a role in regulating the transcription of AR targets (PubMed:18656483). [The UniProt Consortium]
Keywords: Anti-ZNF451, Anti-Zinc finger protein 451, Anti-E3 SUMO-protein ligase ZNF451, Anti-Coactivator for steroid receptors
Supplier: Bethyl Laboratories
Supplier-Nr: A305-177A-T


Application: WB, IP
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human (Expected: Mouse)
Immunogen: synthetic peptide. The epitope recognized by A305-177A-T maps to a region between residue 1011 to 1061 of human Zinc finger protein 451 using the numbering given in entry Q9Y4E5.2 (GeneID 26036).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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