Anti-ZFP91 / Zinc finger protein 91

In 1X PBS, pH 7.4, with 0.09% sodium azide. ZFP91 belongs to a family of proteins called zinc finger proteins, which are known for their ability to bind to specific DNA sequences and regulate gene expression. ZFP91 contains zinc finger domains that enable it to target and bind to DNA, allowing it to modulate the activity of genes involved in biological processes. Studies have shown that ZFP91 plays a crucial role in diverse cellular functions, such as cell growth, proliferation, and differentiation. Additionally, research has revealed that ZFP91 is involved in the regulation of immune responses and inflammation, highlighting its significance in maintaining a healthy immune system. Protein function: Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'- linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF- kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis. [The UniProt Consortium]