Anti-Zebrafish ILF2 / Interleukin enhancer-binding factor 2 / NF45

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Interleukin enhancer-binding factor 2, also called 'Nuclear factor of activated T-cells 45 kDa,' is a protein that in humans is encoded by the ILF2 gene. The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. Protein function: Appears to function predominantly as a heterodimeric complex with ILF3. This complex may function to regulate transcription of undefined genes. [The UniProt Consortium]