Anti-Zebrafish Cxcl8a / Il-8

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cxcl8a, also known as Il-8 like a, is a chemokine that plays a key role in mediating the immune response, particularly by promoting the recruitment and activation of neutrophils. In zebrafish, Cxcl8a is a functional homolog of mammalian interleukin eight and is critical for the early innate immune defense against infection and tissue injury.Cxcl8a is produced by various cell types in response to inflammatory stimuli and acts through Cxcr receptors to direct the migration of neutrophils to sites of inflammation. In zebrafish embryos and larvae, Cxcl8a expression is rapidly upregulated following bacterial challenge, physical injury, or exposure to immune-modulating compounds.Due to the transparency and genetic tractability of zebrafish, Cxcl8a is widely used as a model to study inflammation, immune cell dynamics, and host pathogen interactions in vivo. It serves as a valuable biomarker for inflammation and is an important tool for investigating the effects of immunomodulatory drugs and environmental stressors.