Anti-ZC3HC1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA024023.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA024023.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that... more

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Product information "Anti-ZC3HC1"

Protein function: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to rat: 86%

Keywords:	Anti-NIPA, Anti-hNIPA, Anti-ZC3HC1, Anti-HSPC216, Anti-Zinc finger C3HC-type protein 1, Anti-Nuclear-interacting partner of ALK, Anti-Nuclear-interacting partner of anaplastic lymphoma kinase
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA024023

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IQVHVTACIL SVCGWACSSS LESMQLSLIT CSQCMRKVGL WGFQQIESSM TDLDASFGLT SSPIPGLEGR PERLPLVPES PRRMMTRSQD (ATA-APrEST74879)