Anti-ZBTB38

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA059378.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA059378.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Transcriptional regulator with bimodal DNA-binding specificity. Binds with a... more

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Product information "Anti-ZBTB38"

Protein function: Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner (PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner, represses expression of MCM10 which plays an important role in DNA-replication (PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 64% and to rat: 68%

Keywords:	Anti-Zinc finger and BTB domain-containing protein 38
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA059378

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EHSYAVSSVA EAYRSQPVRE HDGSSPGNTG KENCEALAAK PKTCRKPKTF SIPQDSDSAT ENIPPPPVSN LEVNQERSPQ PAAVLTRSKS PNNEGDV (ATA-APrEST91996)