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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| NEO-9189-MSM3-P1ABX | 100 µg | - | - |
Request delivery time estimate |
704.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Nucleus, PML... more
Product information "Anti-ZBED1 / DREF, clone PCRP-ZBED1-1E1"
Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Nucleus, PML body. Positive Control: HeLa or HepG2 cells. Chromosome Location: Xp22.33/Yp11.31. Protein Function: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase which sumoylates CHD3/Mi2-alpha, causing its release from DNA (PubMed:27068747). This results in suppression of CHD3/Mi2-alpha transcription repression, increased recruitment of RNA polymerase II to gene promoters and positive regulation of transcription including H1-5 and ribosomal proteins such as: RPS6, RPL10A, and RPL12 (PubMed:12663651, PubMed:17209048, PubMed:17220279, PubMed:27068747). The resulting increased transcriptional activity drives cell proliferation (PubMed:12663651, PubMed:17220279). Binds to 5'-TGTCG[CT]GA[CT]A-3' consensus sequences in gene promoters of ribosomal proteins (PubMed:12663651, PubMed:17209048, PubMed:17220279, PubMed:27068747) , (Microbial infection) Binds to human adenovirus gene promoters and contributes to transcriptional repression and virus growth inhibition during early stages of infection [The Uniprot Consortium]
| Keywords: | Anti-ZBED1, Anti-dREF homolog, Anti-E3 SUMO-protein ligase ZBED1, Anti-Putative Ac-like transposable element, Anti-Zinc finger BED domain-containing protein 1, Anti-DNA replication-related element-binding factor, 559 |
| Supplier: | NeoBiotechnologies |
| Supplier-Nr: | 9189-MSM3ABX |
Properties
| Application: | FC, IF, WB |
| Antibody Type: | Monoclonal |
| Clone: | PCRP-ZBED1-1E1 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| MW: | 86 kD |
| Format: | Purified |
Database Information
| KEGG ID : | K24637 | Matching products |
| UniProt ID : | O96006 | Matching products |
| Gene ID : | GeneID 9189 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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