Anti-ZBED1

Anti-ZBED1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA066112.25 25 µl

7 - 10 business days*

369.00€
ATA-HPA066112.100 100 µl

7 - 10 business days*

491.00€
 
Rabbit Polyclonal ZBED1 Antibody against Human zinc finger BED-type containing 1. Validated for... more
Product information "Anti-ZBED1"
Rabbit Polyclonal ZBED1 Antibody against Human zinc finger BED-type containing 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000034269: 26%, ENSRNOG00000061928: 24%. Protein function: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase which sumoylates CHD3/Mi2-alpha, causing its release from DNA (PubMed:27068747). This results in suppression of CHD3/Mi2-alpha transcription repression, increased recruitment of RNA polymerase II to gene promoters and positive regulation of transcription including H1-5 and ribosomal proteins such as: RPS6, RPL10A, and RPL12 (PubMed:12663651, PubMed:17209048, PubMed:17220279, PubMed:27068747). The resulting increased transcriptional activity drives cell proliferation (PubMed:12663651, PubMed:17220279). Binds to 5'- TGTCG[CT]GA[CT]A-3' consensus sequences in gene promoters of ribosomal proteins (PubMed:12663651, PubMed:17209048, PubMed:17220279, PubMed:27068747). [The UniProt Consortium]
Keywords: Anti-ZBED1, Anti-dREF homolog, Anti-E3 SUMO-protein ligase ZBED1, Anti-Putative Ac-like transposable element, Anti-Zinc finger BED domain-containing protein 1, Anti-DNA replication-related element-binding factor
Supplier: Atlas Antibodies
Supplier-Nr: HPA066112

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: PPVKKLMRTS TPPPASVINN MLAEIFCQTG GVEDQEEWHA QVVEELSNFK SQKVLGLNED PLKWWSDRLA LFPLLPKVLQ
Format: Affinity Purified

Handling & Safety

Storage: -20°C (+4 °C for short term storage)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-ZBED1"
Write a review
or to review a product.
Viewed