Anti-XRN1, clone 1647CT536.85.48

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-F53814-0.05ML	50 µl		-	-	3 - 10 business days*		326.00€
NSJ-F53814-0.2ML	200 µl		-	-	3 - 10 business days*		702.00€

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In 1X PBS, pH 7.4, with 0.09% sodium azide. 5'-3' Exoribonuclease 1 is a major 5'-3'... more

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Product information "Anti-XRN1, clone 1647CT536.85.48"

In 1X PBS, pH 7.4, with 0.09% sodium azide. 5'-3' Exoribonuclease 1 is a major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS). Protein function: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA. Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS). [The UniProt Consortium]

Keywords:	Anti-SEP1, Anti-XRN1, EC=3.1.13.-, Anti-5'-3' exoribonuclease 1, Anti-Strand-exchange protein 1 homolog, XRN1 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	F53814

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	1647CT536.85.48
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	A human recombinant protein corresponding to amino acids 1455-1706
Format:	Purified