Anti-XPD

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-658A-T	10 µl (10 µg)		-		3 - 7 business days*		165.00€
A303-658A	100 µl (100 µg)		-		3 - 7 business days*		586.00€

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Protein function: ATP-dependent 5'-3' DNA helicase, component of the core- TFIIH basal... more

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Product information "Anti-XPD"

Protein function: ATP-dependent 5'-3' DNA helicase, component of the core- TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers. [The UniProt Consortium]

Keywords:	Anti-XPD, Anti-CXPD, Anti-ERCC2, Anti-BTF2 p80, Anti-TFIIH p80, EC=3.6.4.12, Anti-TFIIH 80 kDa subunit, Anti-DNA excision repair protein ERCC-2, Anti-DNA repair protein complementing XP-D cells, Anti-Basic transcription factor 2 80 kDa subunit
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-658A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	synthetic peptide. The epitope recognized by A303-658A-T maps to a region between residue 710 and 760 of human Xeroderma Pigmentosum Complementary Group D, using the numbering given in entry NP_000391.1 (GeneID 2068).
Format:	Antigen Affinity Purified