Anti-XPC

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG56404.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Involved in global genome nucleotide excision repair (GG-NER) by acting as... more

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Product information "Anti-XPC"

Protein function: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA- binding activity. [The UniProt Consortium]

Keywords:	Anti-XPC, Anti-XPCC, Anti-p125, Anti-DNA repair protein complementing XP-C cells, Anti-Xeroderma pigmentosum group C-complementing protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56404

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant protein of Human XPC
MW:	106 kD
Format:	Antigen Affinity Purified