Anti-WWP1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA023180.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA023180.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2... more

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Product information "Anti-WWP1"

Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 82%

Keywords:	Anti-AIP5, Anti-WWP1, Anti-Tiul1, EC=2.3.2.26, Anti-WW domain-containing protein 1, Anti-Atrophin-1-interacting protein 5, Anti-TGIF-interacting ubiquitin ligase 1, Anti-HECT-type E3 ubiquitin transferase WWP1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA023180

Properties

Application:	IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TIDLKQALLI HNRKLERVKE QLKLSLENKN GIAQTGELTV VLDGLVIEQE NITNCSSSPT IEIQENGDAL HENGEPSART TARLAVEGTN GIDNHV (ATA-APrEST76231)