Anti-WNK3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-877A-T	10 µl (2 µg)		-		2 - 8 business days*		178.00€
A301-877A	100 µl		-		2 - 8 business days*		630.00€

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Protein function: Serine/threonine kinase which plays an important role in the regulation of... more

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Product information "Anti-WNK3"

Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913, PubMed:16275911, PubMed:16357011). Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway (PubMed:18768590). Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. [The UniProt Consortium]

Keywords:	Anti-WNK3, Anti-KIAA1566, EC=2.7.11.1, Anti-Protein kinase with no lysine 3, Anti-Protein kinase lysine-deficient 3, Anti-Serine/threonine-protein kinase WNK3
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-877A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-877A-T maps to a region between residue 1 and 50 of human WNK lysine deficient protein kinase 3 using the numbering given in entry NP_001002838.1 (GeneID 65267).
Format:	Antigen Affinity Purified