Anti-Wilms' Tumor, clone WT49 (monoclonal) [Mouse]

Anti-Wilms' Tumor, clone WT49 (monoclonal) [Mouse]
Item number Size Datasheet Manual SDS Delivery time Quantity Price
MON-MONX11064 1 ml - -

10 - 15 business days*

880.00€
 
MONX11064 is recommended for the detection of the Wilms' tumor protein in normal and tumor... more
Product information "Anti-Wilms' Tumor, clone WT49 (monoclonal) [Mouse]"
MONX11064 is recommended for the detection of the Wilms' tumor protein in normal and tumor tissues. Protein function: Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921). [The UniProt Consortium]
Keywords: Anti-WT1, Anti-WT33, Anti-Wilms tumor protein, Mouse anti-Wilms' Tumor, clone WT49 (monoclonal)
Supplier: MONOSAN
Supplier-Nr: MONX11064

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: WT49
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: A prokaryotic recombinant protein containing 1-181 amino acids of the N-terminal of the Wilms' Tumor protein.

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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