Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-561A-T 10 µl (10 µg) -

3 - 9 business days

A301-561A 100 µl (100 µg) -

3 - 9 business days

Protein function: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,... more
Product information "Anti-WDR77/MEP50"
Protein function: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. [The UniProt Consortium]
Keywords: Anti-MEP50, Anti-WDR77, Anti-MEP-50, Anti-HKMT1069, Anti-p44/Mep50, Anti-Methylosome protein 50, Anti-Androgen receptor cofactor p44, Anti-WD repeat-containing protein 77
Supplier: Bethyl Laboratories
Supplier-Nr: A301-561A-T


Application: IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Bovine, Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A301-561A-T maps to a region between residue 1 and 50 of human WD repeat domain 77 (methylosome protein 50) using the numbering given in entry NP_077007.1 (GeneID 79084).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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