Anti-WDR24

Anti-WDR24
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA039506.25 25 µl -

7 - 10 business days*

246.00€
ATA-HPA039506.100 100 µl -

7 - 10 business days*

491.00€
 
Protein function: As a component of the GATOR subcomplex GATOR2, functions within the amino... more
Product information "Anti-WDR24"
Protein function: As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: Anti-GATOR complex protein WDR24, Anti-WD repeat-containing protein 24
Supplier: Atlas Antibodies
Supplier-Nr: HPA039506

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: EQFVEKLNLR VGRKPSLNLS CADVVWHQMD ENLLATAATN GVVVTWNLGR PSRNKQDQLF TEHKRTVNKV CFHPTEAHVL LSGSQDGFMK CFDLRRKDSV ST (ATA-APrEST80894)

Database Information

KEGG ID : K20408 | Matching products
UniProt ID : Q96S15 | Matching products
Gene ID : GeneID 84219 | Matching products
Protein Atlas Nr. : ENSG00000127580

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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