Anti-VRK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA000660.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA000660.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Serine/threonine kinase involved in Golgi disassembly during the cell cycle:... more

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Product information "Anti-VRK1"

Protein function: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain- containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 90% and to rat: 92%

Keywords:	Anti-VRK1, EC=2.7.11.1, Anti-Vaccinia-related kinase 1, Anti-Serine/threonine-protein kinase VRK1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA000660

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KAAQAGRQSS AKRHLAEQFA VGEIITDMAK KEWKVGLPIG QGGFGCIYLA DMNSSESVGS DAPCVVKVEP SDNGPLFTEL KFYQRAAKPE QIQKWIRTRK LKYLGVPKYW GSGLHDKNGK SYRFMIMDRF GSDLQKI (ATA-APrEST70404)