Anti-VRK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-268A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A305-268A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Serine/threonine kinase involved in Golgi disassembly during the cell cycle:... more

Close menu

Product information "Anti-VRK1"

Protein function: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr- 18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity. [The UniProt Consortium]

Keywords:	Anti-VRK1, EC=2.7.11.1, Anti-Vaccinia-related kinase 1, Anti-Serine/threonine-protein kinase VRK1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-268A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, gorilla, chimpanzee, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A305-268A-T maps to a region between residue 1 to 50 of human Serine/threonine-protein kinase VRK1 using the numbering given in entry Q99986.1 (GeneID 7443).
Format:	Antigen Affinity Purified