Anti-VPS25

Polyclonal Antibody against Human VPS25, Gene description: vacuolar protein sorting 25 homolog, Alternative Gene Names: DERP9, EAP20, MGC10540, Validated applications: ICC, Uniprot ID: Q9BRG1, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses. [The UniProt Consortium] Mouse gene identity: 98% Rat gene identity: 98%