Anti-von Willebrand Factor / vWF, clone F8/86

Anti-von Willebrand Factor / vWF, clone F8/86
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3233-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3233-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. von Willebrand Factor... more
Product information "Anti-von Willebrand Factor / vWF, clone F8/86"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Protein function: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. [The UniProt Consortium]
Keywords: Anti-VWF, Anti-F8VWF, von Willebrand Factor / vWF Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3233-20UG

Properties

Application: FC, IF, IHC
Antibody Type: Monoclonal
Clone: F8/86
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Human plasma vWF protein was used as the immunogen for this von Willebrand Factor antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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