Anti-von Willebrand Factor (vWF), clone IIIE2.34

Anti-von Willebrand Factor (vWF), clone IIIE2.34
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2929SAF-100UG 100 µg - -

3 - 10 business days

1 mg/ml in sterile PBS, BSA free, sodium azide free. von Willebrand Factor (vWF) is a multimeric... more
Product information "Anti-von Willebrand Factor (vWF), clone IIIE2.34"
1 mg/ml in sterile PBS, BSA free, sodium azide free. von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Protein function: Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. [The UniProt Consortium]
Keywords: Anti-VWF, Anti-F8VWF, von Willebrand Factor Antibody (vWF)
Supplier: NSJ Bioreagents
Supplier-Nr: V2929SAF-100UG


Application: FC, IF, WB, IP, IHC (paraffin)
Antibody Type: Monoclonal
Clone: IIIE2.34
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A partial vWF recombinant protein (aa 845-949)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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