Anti-Visfatin

Anti-Visfatin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-779A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A300-779A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: Catalyzes the condensation of nicotinamide with 5-... more
Product information "Anti-Visfatin"
Protein function: Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. [The UniProt Consortium]
Keywords: Anti-PBEF, Anti-NAMPT, Anti-Nampt, Anti-Visfatin, Anti-NAmPRTase, EC=2.4.2.12, Anti-Pre-B cell-enhancing factor, Anti-Pre-B-cell colony-enhancing factor 1, Anti-Nicotinamide phosphoribosyltransferase
Supplier: Bethyl Laboratories
Supplier-Nr: A300-779A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan, gorilla, chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A300-779A-T maps to a region between residue 450 and the C-terminus (residue 491) of human Visfatin (PBEF/NAMPT) using the numbering given in entry NP_005737.1 (GeneID 10135).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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