Anti-Vimentin, clone VM1170

Anti-Vimentin, clone VM1170
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2928SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb reacts with a 58kDa protein... more
Product information "Anti-Vimentin, clone VM1170"
1 mg/ml in sterile PBS, BSA free, sodium azide free. This mAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin, keratin, neurofilament, and glial fibrillary acid protein. Anti-vimentin alone is of limited value as a diagnostic tool, however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent. Protein function: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally. [The UniProt Consortium]
Keywords: Anti-VIM, Anti-Vimentin, Vimentin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2928SAF-100UG

Properties

Application: FC, IF, WB, IHC (paraffin)
Antibody Type: Monoclonal
Clone: VM1170
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant full-length human Vimentin protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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