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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABS-RN-17283.50 | 50 µl | - | - |
10 - 15 business days* |
232.00€
|
||
| ABS-RN-17283.100 | 100 µl | - | - |
10 - 15 business days* |
332.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide.... more
Product information "Anti-VHL (recombinant antibody)"
Formulation: Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide. Identity-Mouse (%): . Homologies: . IHC Verification: -. WB Verification: -. IP Verification: succeed. IF Verification: -. FC Verification: -. IP-MS Verification: -. Cross reactivity: Not tested. Sandwich ELISA Verification: -. Antigen ID: ABS-P00030CA. Recombinant Antibody: Protein Function: Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex (PubMed:10944113, PubMed:17981124, PubMed:19584355). Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions (PubMed:10944113, PubMed:17981124). Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases (PubMed:10944113, PubMed:17981124). Ubiquitinates, in an oxygen-responsive manner, ADRB2 (PubMed:19584355). Acts as a negative regulator of mTORC1 by promoting ubiquitination and degradation of RPTOR (PubMed:34290272) [The Uniprot Consortium]
| Keywords: | Anti-VHL, Anti-pVHL, Anti-Protein G7, Anti-von Hippel-Lindau disease tumor suppressor, Recombinant VHL Antibody |
| Supplier: | Absea |
| Supplier-Nr: | RN-17283 |
Properties
| Application: | IP/ChIP |
| Antibody Type: | Monoclonal |
| Clone: | K24121_21G9 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| Immunogen: | Recombinant uman VHL&ELOB&ELOC |
| Purity: | >85% |
| Format: | Solution |
Database Information
| KEGG ID : | K03871 | Matching products |
| UniProt ID : | P40337 | Matching products |
| Gene ID : | GeneID 7428 | Matching products |
Handling & Safety
| Storage: | +4°C (-20 °C for long term storage) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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