Anti-VEGF

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R31500 100 µg - -

3 - 10 business days*

755.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. VEGF is the only mitogen that specifically... more
Product information "Anti-VEGF"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. VEGF is the only mitogen that specifically acts on endothelial cells. It may be a major regulator of tumor angiogenesis in vivo. It is structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. VEGF induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. And this gene also can regulate haematopoietic stem cell survival by an internal autocrine loop mechanism. WhatÆs more, it also stimulates neurogenesis in vitro and in vivo. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. [The UniProt Consortium]
Keywords: Anti-VPF, Anti-VEGF, Anti-VEGFA, Anti-VEGF-A, Anti-Vascular permeability factor, Anti-Vascular endothelial growth factor A, VEGF Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R31500

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat
Immunogen: Human recombinant protein, A isoform (AA 27-191) was used as the immunogen for this VEGF antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-VEGF"
Write a review
or to review a product.
Viewed