Anti-VCAM1, clone B-K9

Anti-VCAM1, clone B-K9
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2924SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 110kDa, identified... more
Product information "Anti-VCAM1, clone B-K9"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. L1CAM serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This mAb inhibits the binding of leukocytes to L1CAM on stimulated endothelial cells. Protein function: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [The UniProt Consortium]
Keywords: Anti-CD106, Anti-VCAM1, Anti-L1CAM, Anti-VCAM-1, Anti-V-CAM 1, Anti-INCAM-100, Anti-Vascular cell adhesion protein 1, VCAM-1 Antibody (L1CAM)
Supplier: NSJ Bioreagents
Supplier-Nr: V2924SAF-100UG

Properties

Application: FC, IF, FA (blocking)
Antibody Type: Monoclonal
Clone: B-K9
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Activated human umbilical vein endothelial cells (HUVEC)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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