Anti-Vasopressin (Arg)

Arginine vasopressin (AVP), also known as vasopressin, argipressin or antidiuretic hormone (ADH), is a hormone found in most mammals, including humans. Vasopressin is a peptide hormone that controls the reabsorption of molecules in the tubules of the kidneys by affecting the tissue's permeability. It also increases peripheral vascular resistance, which in turn increases arterial blood pressure. It plays a key role in homeostasis, and the regulation of water, glucose, and salts in the blood. It is derived from a preprohormone precursor that is synthesized in the hypothalamus and stored in vesicles at the posterior pituitary. Most of it is stored in the posterior pituitary to be released into the bloodstream. However, some AVP is also released directly into the brain. Applications: Suitable for use in Immunohistochemistry, Immunocytochemistry, Western Blot and RIA. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: 1:5000-1:10,000. Using 18-24 hour incubation with formalin, Bouin's or Zamboni's fixed tissue. Will react on paraffin embedded tissue. , Immunocytochemistry: 1:1000-1:200,000. Using 18-24 hour incubation with fetal rat neurons., Western Blot: 1:1000, RIA: 1:30,000-1:750,000, Sensitivity: <1pg/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.