Anti-Vasoactive Intestinal Peptide (VIP)

Located in the nerve fibers in the central and peripheral nervous system, VIP is probably acting as a neurotransmitter. The Verner-Morrison or Water Diarrhea Hypokalemia and Achlorhydria (WDHA) syndrome is a characteristic clinical syndrome associated with overproduction of VIP from endocrine tumors. VIP-producing tumors are usually neuroblastomas or endocrine tumors in the pancreas. The localization of the antigen is extracellular and cytoplasmic. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.