Anti-VAC14

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES19716.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES19716.100	100 µl		-	-	10 - 14 business days*		290.00€

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Protein function: Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates... more

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Product information "Anti-VAC14"

Protein function: Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Pentamerizes into a star-shaped structure and nucleates the assembly of the complex. The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3- phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P) (PubMed:33098764). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes. [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Endosome membrane . Microsome membrane . Mainly associated with membranes of the late endocytic pathway.

Keywords:	Anti-VAC14, Anti-TAX1BP2, Anti-Protein VAC14 homolog, Anti-Tax1-binding protein 2, VAC14 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES19716

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthesized peptide derived from human VAC14 AA range: 569-619
Format:	Purified