Anti-utp25

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1: 64,000 confirmed by ELISA, 3. WB positive with the immunogen protein (not applicable for synthetic peptide). Applications: ELISA, WB (positive for the recombinant immunogen protein/peptide). Buffer: Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Protein function: Component of the ribosomal small subunit processome for the biogenesis of ribosomes, functions in pre-ribosomal RNA (pre-rRNA) processing (PubMed:28263972). Essential for embryonic development in part through the regulation of p53 pathway. Required for the expansion growth of intestine, liver and exocrine pancreas, but not endocrine pancreas. May not play a major role during the early stage of endodermal organogenesis. Also involved in the sympathetic neuronal development (PubMed:28263972). Triggers the degradation of p53/TP53 and Delta113p53 isoform in a ubiquitination pathway independent way (PubMed:23357851). Mediates, with CAPN3, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329). [The UniProt Consortium]