Anti-USP45

Anti-USP45
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES7798.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES7798.100 100 µl - -

10 - 14 business days*

290.00€
 
The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of... more
Product information "Anti-USP45"
The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1. [provided by RefSeq, Sep 2016], Protein function: Catalyzes the deubiquitination of SPDL1 (PubMed:30258100). Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites (PubMed:25538220). May be involved in the maintenance of photoreceptor function (PubMed:30573563). May play a role in normal retinal development. Plays a role in cell migration (PubMed:30258100). [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Photoreceptor inner segment . Cytoplasm . Nucleus .
Keywords: Anti-USP45, Anti-Ubiquitin thioesterase 45, Anti-Deubiquitinating enzyme 45, Anti-Ubiquitin carboxyl-terminal hydrolase 45, Anti-Ubiquitin-specific-processing protease 45, USP45 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES7798

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: The antiserum was produced against synthesized peptide derived from human USP45. AA range:301-350
MW: 90 kD
Format: Antiserum

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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