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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG43099.50 | 50 µg | - | - |
10 - 15 business days* |
551.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Deubiquitinase that plays a key regulatory role in the spindle assembly... more
Product information "Anti-USP44"
Protein function: Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B (H2BK120ub1) ubiquitination. [The UniProt Consortium]
| Keywords: | Anti-USP44, Anti-Ubiquitin thioesterase 44, Anti-Ubiquitin thioesterase 44, Anti-Deubiquitinating enzyme 44, Anti-Deubiquitinating enzyme 44, Anti-Ubiquitin carboxyl-terminal hydrolase 44, Anti-Ubiquitin carboxyl-terminal hydrolase 44, Anti-Ubiquitin-spec |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG43099 |
Properties
| Application: | FC, ICC, IF, IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | Recombinant protein corresponding to R211-S712 of Human USP44 |
| MW: | 81 kD |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K11834 | Matching products |
| UniProt ID : | Q9H0E7 | Matching products |
| Gene ID : | GeneID 84101 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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