Anti-USP20

Anti-USP20
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R34186-100UG 100 µg - -

3 - 10 business days*

755.00€
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more
Product information "Anti-USP20"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Ubiquitin specific protease 20 Protein function: Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. [The UniProt Consortium]
Keywords: Anti-hVDU2, Anti-USP20, Anti-KIAA1003, EC=3.4.19.12, Anti-Ubiquitin thioesterase 20, Anti-Deubiquitinating enzyme 20, Anti-Ubiquitin carboxyl-terminal hydrolase 20, Anti-VHL-interacting deubiquitinating enzyme 2, USP20 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R34186

Properties

Application: WB, IHC, ELISA (peptide)
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Species reactivity: human
Immunogen: Amino acids HGEQKIEAETRAV were used as the immunogen for this USP20 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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