Anti-USP16

Anti-USP16
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA018279.25 25 µl

7 - 10 business days*

369.00€
ATA-HPA018279.100 100 µl

7 - 10 business days*

491.00€
 
Rabbit Polyclonal USP16 Antibody against Human ubiquitin specific peptidase 16. Validated for... more
Product information "Anti-USP16"
Rabbit Polyclonal USP16 Antibody against Human ubiquitin specific peptidase 16. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000025616: 65%, ENSRNOG00000001598: 64%. Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. [The UniProt Consortium]
Keywords: Anti-MSTP039, Anti-Ubiquitin thioesterase 16, Anti-Deubiquitinating enzyme 16, Anti-Ubiquitin-processing protease UBP-M, Anti-Ubiquitin carboxyl-terminal hydrolase 16, Anti-Ubiquitin-specific-processing protease 16
Supplier: Atlas Antibodies
Supplier-Nr: HPA018279

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: PSGTSKHLQK KAKKQAKKQA KNQRRQQKIQ GKVLHLNDIC TIDHPEDSEY EAEMSLQGEV NIKSNHISQE GVMHKEYCVN
Format: Affinity Purified

Handling & Safety

Storage: -20°C (+4 °C for short term storage)
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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