Anti-Uroplakin 3B (UPK3B) (Marker of Mesothelial & Umbrella Cells), clone MSVA-736M

Formulation: Purified Ab with BSA and Azide. Cellular Localization: Cell surface. Positive Control: Urinary bladder: A moderate to strong membranous Upk3b immunostaining should be seen in umbrella cells of the normal urothelium (the staining is usually limited to apical surface membrane of umbrella cells). Chromosome Location: 19q13.12. Protein Function: Component of the asymmetric unit membrane (AUM). a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity) [The Uniprot Consortium]