Anti-Uroguanylin (aa1-8) (UGN, Guanylate Cyclase Activator 2B, GUCA2B)

Uroguanylin is a 16aa peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia. Applications: Suitable for use in ELISA, Immunohistochemistry, Western Blot and RIA. Other applications not tested. Recommended Dilutions: ELISA: 1:2000, Immunohistochemistry (Acrylic resin): 1:800, Western Blot: 1:1000, RIA: 1:10,000, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.