Anti-ugpB

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1: 64,000 confirmed by ELISA, 3. WB positive with the immunogen protein (not applicable for synthetic peptide). Applications: ELISA, WB (positive for the recombinant immunogen protein/peptide). Buffer: Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Protein function: Part of the ABC transporter complex UgpBAEC involved in sn- glycerol-3-phosphate (G3P) import (PubMed:23013274, PubMed:2842304). Can also transport glycerophosphoryl diesters, which are hydrolyzed to G3P and alcohol during transport (PubMed:2842304). The G3P moiety can be detected in the cytoplasm whereas the corresponding alcohol is usually found in the culture medium (PubMed:2842304). Binds G3P and glycerophosphocholine, but not glycerol-2-phosphate (PubMed:23013274). It was proposed by Yang et al that the complex could also transport glycerol-2-phosphate (G2P) in vivo, but as it was shown later by Wuttge et al that UgpB does not bind G2P, this transport activity is questioned (PubMed:19429609, PubMed:23013274). G2P might be converted in the periplasm to G3P before its transport (PubMed:23013274). [The UniProt Consortium]