Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-456A-T 20 µl (2 blots) -

3 - 9 business days*

A303-456A-M 100 µl (10 blots) -

3 - 9 business days*

A303-456A 100 µl (20 µg) -

3 - 9 business days*

Protein function: E3 protein ligase that mediates ufmylation, the covalent attachment of the... more
Product information "Anti-UFL1"
Protein function: E3 protein ligase that mediates ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, a post-translational modification on lysine residues of proteins that may play a crucial role in a number of cellular processes. Mediates DDRGK1 ufmylation and may regulate the proteasomal degradation of DDRGK1 and CDK5RAP3 thereby modulating NF-kappa-B signaling (PubMed:20018847, PubMed:20164180, PubMed:20228063, PubMed:25219498). May also through TRIP4 ufmylation play a role in nuclear receptors-mediated transcription (PubMed:25219498). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress (PubMed:23152784). [The UniProt Consortium]
Keywords: Anti-E3 UFM1-protein ligase 1, Anti-Novel LZAP-binding protein, Anti-E3 UFM1-protein transferase 1, Anti-Regulator of C53/LZAP and DDRGK1
Supplier: Bethyl Laboratories
Supplier-Nr: A303-456A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Bovine)
Immunogen: synthetic peptide. The epitope recognized by A303-456A-T maps to a region between residue 744 and 794 of human E3 UFM1-Protein Ligase 1 using the numbering given in entry NP_056138.1 (GeneID 23376).
Format: Antigen Affinity Purified

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