Anti-UBQLN4/CIP75/Ubiquilin 4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-237A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A305-237A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Plays a role in the regulation of protein degradation via the... more

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Product information "Anti-UBQLN4/CIP75/Ubiquilin 4"

Protein function: Plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome (Ref. 6). Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1. Acts as an adapter protein that recruits UBQLN1 to the autophagy machinery. Mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205). [The UniProt Consortium]

Keywords:	Anti-A1Up, Anti-CIP75, Anti-UBQLN4, Anti-C1orf6, Anti-Ubiquilin-4, Anti-Connexin43-interacting protein of 75 kDa, Anti-Ataxin-1 interacting ubiquitin-like protein, Anti-Ataxin-1 ubiquitin-like-interacting protein A1U
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-237A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine, pig, orangutan, rhesus monkey, chimpanzee, cetartiodactyla, white-tufted-ear marmoset)
Immunogen:	synthetic peptide. The epitope recognized by A305-237A-T maps to a region between residue 1 to 50 of human Ubiquilin-4 using the numbering given in entry Q9NRR5.2 (GeneID 56893).
Format:	Antigen Affinity Purified