Anti-UBP35

Anti-UBP35
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ELK-ES10419.50 50 µl - -

10 - 14 business days*

173.00€
ELK-ES10419.100 100 µl - -

10 - 14 business days*

290.00€
 
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a... more
Product information "Anti-UBP35"
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in testis, pancreas and skeletal muscle., Protein function: Deubiquitinase that plays a role in different processes including cell cycle regulation, mitophagy or endoplasmic reticulum stress (PubMed:26348204, PubMed:29449677, PubMed:37004621). Inhibits TNFalpha-induced NF-kappa-B activation through stabilizing TNIP2 protein via deubiquitination (PubMed:26348204). Plays an essential role during mitosis by deubiquitinating and thereby regulating the levels of Aurora B/AURKB protein (PubMed:29449677). In addition, regulates the protein levels of other key component of the chromosomal passenger complex (CPC) such as survivin/BIRC5 or Borealin/CDCA8 by enhancing their stability (PubMed:34438346). Regulates the degradation of mitochondria through the process of autophagy termed mitophagy (PubMed:25915564). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization:
Keywords: Anti-USP35, Anti-KIAA1372, Anti-Ubiquitin thioesterase 35, Anti-Deubiquitinating enzyme 35, Anti-Ubiquitin carboxyl-terminal hydrolase 35, Anti-Ubiquitin-specific-processing protease 35, UBP35 rabbit pAb
Supplier: ELK Biotechnology
Supplier-Nr: ES10419

Properties

Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, rat, mouse,
Immunogen: Synthesized peptide derived from part region of human protein
MW: 111 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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