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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES10440.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES10440.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein... more
Product information "Anti-UBE2O"
catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins.,pathway:Protein modification, protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,tissue specificity:Predominantly expressed in skeletal muscle and heart., Protein function: E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins (PubMed:23455153, PubMed:24703950). Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 activity (PubMed:23381138). Acts as a positive regulator of BMP7 signaling by mediating monoubiquitination of SMAD6, thereby regulating adipogenesis (PubMed:23455153). Mediates monoubiquitination at different sites of the nuclear localization signal (NLS) of BAP1, leading to cytoplasmic retention of BAP1. Also able to monoubiquitinate the NLS of other chromatin-associated proteins, such as INO80 and CXXC1, affecting their subcellular location (PubMed:24703950). Acts as a regulator of retrograde transport by assisting the TRIM27:MAGEL2 E3 ubiquitin ligase complex to mediate 'Lys-63'-linked ubiquitination of WASHC1, leading to promote endosomal F-actin assembly (PubMed:23452853). [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cytoplasm . Nucleus . Mainly localizes to the cytoplasm.
Keywords: | Anti-UBE2O, Anti-KIAA1734, Anti-Ubiquitin-protein ligase O, Anti-Ubiquitin carrier protein O, Anti-Ubiquitin-conjugating enzyme E2 O, Anti-Ubiquitin-conjugating enzyme E2-230K, Anti-Ubiquitin-conjugating enzyme E2 of 230 kDa, UBE2O rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES10440 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Synthesized peptide derived from part region of human protein |
MW: | 142 kD |
Format: | Purified |
Database Information
KEGG ID : | K10581 | Matching products |
UniProt ID : | Q9C0C9 | Matching products |
Gene ID | GeneID 63893 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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