Anti-Tyrosinase-Related Protein-1 / TRP1, clone TYRP1/2340R

Anti-Tyrosinase-Related Protein-1 / TRP1, clone TYRP1/2340R
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3585-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V3585-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Tyrosinase-Related... more
Product information "Anti-Tyrosinase-Related Protein-1 / TRP1, clone TYRP1/2340R"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Tyrosinase-Related Protein-1 / TYRP1 / TRP1 is involved in melanin synthesis. It is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. It is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Protein function: Catalyzes the oxidation of 5,6-dihydroxyindole-2- carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid in the presence of bound Cu(2+) ions (PubMed:28661582). May regulate or influence the type of melanin synthesized (PubMed:22556244, PubMed:16704458). Also to a lower extent, capable of hydroxylating tyrosine and producing melanin. [The UniProt Consortium]
Keywords: Anti-TRP, Anti-TRP1, Anti-TRP-1, Anti-TYRP1, Anti-Catalase B, Anti-DHICA oxidase, Anti-Glycoprotein 75, Anti-Melanoma antigen gp75, Anti-Tyrosinase-related protein 1, Anti-5,6-dihydroxyindole-2-carboxylic acid oxidase, Tyrosinase-Related Protein-1 / TRP1
Supplier: NSJ Bioreagents
Supplier-Nr: V3585

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: TYRP1/2340R
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: A portion of amino acids 257-377 was used as the immunogen for this recombinant TRP1 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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