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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG45770.50 | 50 µg | - | - |
10 - 15 business days* |
501.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Negatively regulates post-translational modifications of tubulin, including... more
Product information "Anti-TTLL12"
Protein function: Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues (PubMed:20162578, PubMed:23251473). Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3) (PubMed:23251473). Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability (PubMed:20162578, PubMed:23251473). During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE (PubMed:28011935). [The UniProt Consortium]
| Keywords: | Anti-TTLL12, Anti-KIAA0153, Anti-Tubulin--tyrosine ligase-like protein 12, Anti-Tubulin--tyrosine ligase-like protein 12, Anti-Inactive tubulin--tyrosine ligase-like protein 12, Anti-Inactive tubulin--tyrosine ligase-like protein 12 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG45770 |
Properties
| Application: | FC, IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant protein containing to human TTLL12 |
| MW: | 74 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K16609 | Matching products |
| UniProt ID : | Q14166 | Matching products |
| Gene ID : | GeneID 23170 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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