Anti-TSHR, clone 1C8, IgG1 Chimeric mAb, biotinylated

Item number	Size	Manual	Delivery time	Price
DIM-DMC101228B.10	10 µg	-	7 - 16 business days*	203.00€
DIM-DMC101228B.100	100 µg	-	7 - 16 business days*	980.00€
DIM-DMC101228B.500	500 µg	-	7 - 16 business days*	2,925.00€

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Purified from cell culture supernatant by affinity chromatography. The protein encoded by this... more

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Product information "Anti-TSHR, clone 1C8, IgG1 Chimeric mAb, biotinylated"

Purified from cell culture supernatant by affinity chromatography. The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]. Protein function: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism. [The UniProt Consortium]

Keywords:	The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a c
Supplier:	DIMA
Supplier-Nr:	DMC101228B

Properties

Application:	FC
Antibody Type:	Monoclonal
Conjugate:	Biotin
Host:	Rabbit/Human
Species reactivity:	human
Format:	Lyophilized

Database Information

KEGG ID :	K04249 \| Matching products
UniProt ID :	P16473 \| Matching products
Gene ID :	GeneID 7253 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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