Anti-TSG101

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG40187.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process.... more

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Product information "Anti-TSG101"

Protein function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413). It may also play a role in the extracellular release of microvesicles that differ from the exosomes (PubMed:22315426). [The UniProt Consortium]

Keywords:	Anti-TSG101, Anti-ESCRT-I complex subunit TSG101, Anti-Tumor susceptibility gene 101 protein
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG40187

Properties

Application:	FC, ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide derived from Human TSG101
MW:	44 kD
Format:	Affinity Purified