Anti-TRPS1 (Transcriptional repressor GATA binding 1), recombinant antibody, clone MSVA-512R

Formulation: Purified Ab with BSA and Azide. Cellular Localization: Nucleus. Positive Control: Breast: A strong TRPS1 staining should be seen in luminal breast epithelial cells. (For low-level TRPS1 detection: Testis: A weak nuclear TRPS1 staining should be seen in spermatogonia.). Chromosome Location: 8q23.3. Protein Function: Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes [The Uniprot Consortium]